SNL’s Will Forte On How Huntington’s Disease Has Become A Family Issue
Summary
Will Forte, known for his role as MacGruber on Saturday Night Live, and his brother-in-law Doug Modling, who battles Huntington's Disease, are actively raising awareness about the condition, highlighting its impact and the need for greater understanding.
Key Insights
What is Huntington's Disease and how is it inherited?
Huntington's Disease (HD) is a rare, genetic, neurodegenerative disorder caused by a mutation in the HTT gene, inherited in an autosomal dominant pattern, meaning each child of an affected parent has a 50% chance of inheriting the gene expansion and developing the disease.[6][7]
How does Huntington's Disease affect families beyond the person diagnosed?
HD significantly disrupts family functioning, with high rates of dysfunction including adverse parenting, reduced affective involvement, communication issues, and problem-solving difficulties; family members often experience elevated depression, caregiver burden, and emotional distress, particularly younger caregivers and children at risk of inheriting the gene.[1][2][3]